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Blue rubber bleb nevus syndrome natural history, complications and prognosis
Introduction
Overview
Overview
Common complications of blue rubber bleb nevus syndrome include GI bleeding, Intussusception, and Intestinal perforation.
Natural History, Complications and Prognosis
Natural History, Complications and Prognosis
Natural History
- The symptoms of blue rubber bleb nevus syndrome usually develop in the first decade of life, and start with symptoms such as [1]
Complications
Common complications of blue rubber bleb nevus syndrome include:[2][3][4][5]
- Acute GI bleeding[6]
- Anemia due to bleeding[7]
- Intussusception
- Bowel infarction
- Intestinal torsion
- Necrosis of intestinal mucosa
- Intestinal perforation
- Volvulus
- Stroke
- Abscess formation and
- Even death due to central nervous system involvement.[8]
Prognosis
- Depending on the extent of the blue rubber bleb nevus syndrome at the time of diagnosis, the prognosis may vary.
- Prognosis of the blue rubber bleb nevus syndrome is depend on the following:[9][10]
- Severity of the signs and symptoms at the time of diagnosis
- Vascular malformations size and number
- Vascular malformations locations
- Overall, prognosis is good and patients with blue rubber bleb nevus syndrome have normal lifespan if it diagnosed intime.[11]
References
References
- ↑ Rodrigues D, Bourroul ML, Ferrer AP, Monteiro Neto H, Gonçalves ME, Cardoso SR (2000). “Blue rubber bleb nevus syndrome”. Rev Hosp Clin Fac Med Sao Paulo. 55 (1): 29–34. PMID 10881076.
- ↑ Dwivedi M, Misra SP (2002). “Blue rubber bleb nevus syndrome causing upper GI hemorrhage: a novel management approach and review”. Gastrointestinal Endoscopy. 55 (7): 943–6. PMID 12024162. Retrieved 2012-09-10. Unknown parameter
|month=ignored (help) - ↑ Nahm WK, Moise S, Eichenfield LF, Paller AS, Nathanson L, Malicki DM, Friedlander SF (May 2004). “Venous malformations in blue rubber bleb nevus syndrome: variable onset of presentation”. J. Am. Acad. Dermatol. 50 (5 Suppl): S101–6. doi:10.1016/S0190. PMID 15097941.
- ↑ Jin XL, Wang ZH, Xiao XB, Huang LS, Zhao XY (December 2014). “Blue rubber bleb nevus syndrome: a case report and literature review”. World J. Gastroenterol. 20 (45): 17254–9. doi:10.3748/wjg.v20.i45.17254. PMID 25493043.
- ↑ Feingold RM (2009). “The blue rubber bleb [corrected] nevus syndrome”. J Insur Med. 41 (1): 67–71. PMID 19518008.
- ↑ Dobru D, Seuchea N, Dorin M, Careianu V (September 2004). “Blue rubber bleb nevus syndrome: case report and literature review”. Rom J Gastroenterol. 13 (3): 237–40. PMID 15470538.
- ↑ Lybecker MB, Stawowy M, Clausen N (December 2016). “Blue rubber bleb naevus syndrome: a rare cause of chronic occult blood loss and iron deficiency anaemia”. BMJ Case Rep. 2016. doi:10.1136/bcr-2016-216963. PMID 27999128.
- ↑ Tomelleri G, Cappellari M, Di Matteo A, Zanoni T, Colato C, Bovi P, Moretto G (August 2010). “Blue rubber bleb nevus syndrome with late onset of central nervous system symptomatic involvement”. Neurol. Sci. 31 (4): 501–4. doi:10.1007/s10072-010-0250-4. PMID 20352269.
- ↑ Jin, Xue-Li (2014). “Blue rubber bleb nevus syndrome: A case report and literature review”. World Journal of Gastroenterology. 20 (45): 17254. doi:10.3748/wjg.v20.i45.17254. ISSN 1007-9327.
- ↑ Apak H, Celkan T, Ozkan A, Yildiz I, Aydemir EH, Ozdil S, Kuruoglu S (2004). “Blue rubber bleb nevus syndrome associated with consumption coagulopathy: treatment with interferon”. Dermatology (Basel). 208 (4): 345–8. doi:10.1159/000077846. PMID 15178920.
- ↑ Hernandez, Oscar V.; Blancas, Manuel; Paz, Victor; Moran, Segundo; Hernandez, Luisa (2007). “DIAGNOSIS AND TREATMENT OF BLUE RUBBER BLEB NEVUS SYNDROME WITH DOUBLE BALLOON ENTEROSCOPY AND ENDOSCOPIC ULTRASOUND”. Digestive Endoscopy. 19 (2): 86–89. doi:10.1111/j.1443-1661.2007.00672.x. ISSN 0915-5635.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]