Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Bone marrow disorders
Introduction
For congenital bone marrow disorders, click here.
For acquired bone marrow disorders, click here.
Overview
Overview
Bone marrow disorders are classified into congenital bone marrow disorders and acquired bone marrow disorders.
Definition of Terms
Definition of Terms
- Bone marrow suppression: Reduced numbers of cells in the bone marrow
- Myelosuppression: Reduced number of myeloid lineage cells (RBC, neutrophils, basophils, eosinophils, monocytes, platelets, mastocytes)
- Immunosuppression or lymphosuppression: Reduced number of lymphoid lineage cells (T-cell, B-cell, NK cell)
- Bone marrow proliferation: Increased numbers of cells in the bone marrow
- Myeloproliferation: Increased number of myeloid lineage cells (RBC, neutrophils, basophils, eosinophils, monocytes, platelets, mastocytes)
- Immunoproliferation or lymphoproliferation: Increased number of lymphoid lineage cells (T-cell, B-cell, NK cell)
Classification
Classification
Shown below is an algorithm depicting the different classes of bone marrow disorders.
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| Myelosuppression | Â | Immunosuppression | Â | Myeloproliferation | Â | Immunoproliferation | Â | Multiple lineages | Â | Single lineage | Â | Â | |||||||||||||||||||||||||||||||||||||||
References
References
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Yazan Daaboul, M.D.; Rim Halaby, M.D. [2]; Serge Korjian M.D.