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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Bone or cartilage mass epidemiology and demographics

Introduction

Overview

Overview

Bone and cartilage tumors are uncommon, they represent 0.2% of all neoplasms in general population. The prevalence of bone and cartilage tumors is approximately 0.9 per 100,000 individuals. Bone and cartilage tumors have a bimodal age distribution. These tumors are more frequent in children and adolescents, and older adults. The average age at diagnosis is between 10-25 years old and 60-75 years old. Males are more commonly affected than females, with a 1.5:1 ratio.[1] Bone and cartilage tumors are slightly more common among individuals of Caucasian race.[2]

Epidemiology and Demographics

Epidemiology and Demographics

Prevalence

  • The estimated prevalence of bone and cartilage tumors is 0.2% in general population.[1]
  • The table below summarizes the frequency order of common primary malignant bone and cartilage tumors.
Primary bone malignancy Frequency (%)
Osteosarcoma 35.1
Chondrosarcoma 25.8
Ewing sarcoma 16
Chordoma 8.4
Malignant fibrous histiocytoma 5.7
Unespecifed 1.2
Others 6.4

Incidence

  • The incidence rate for all bone and cartilage malignant tumors is 0.9 per 100,000 persons per year.[1]

Age

  • The age-adjusted incidence rate of malignant bone and cartilage tumors has a bimodal distribution.[1]
  • The first peak of incidence has an average age at diagnosis between 10-25 years.
  • The second peak of incidence has an average age at diagnosis between 60-75 years.

Gender

  • Males are slightly more affected than females. The male-to-female ratio is approximately 1.5 to 1.

Race

  • Bone and cartilage tumors are slightly more common among individuals of Caucasian race.[1]
References

References

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Franchi A (2012). “Epidemiology and classification of bone tumors”. Clin Cases Miner Bone Metab. 9 (2): 92–5. PMC 3476517. PMID 23087718.
  2. ↑ Tubiana-Hulin M (1991). “Incidence, prevalence and distribution of bone metastases”. Bone. 12 Suppl 1: S9–10. PMID 1954049.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]