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Bone or cartilage mass epidemiology and demographics

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]

Overview

Overview

Bone and cartilage tumors are uncommon, they represent 0.2% of all neoplasms in general population. The prevalence of bone and cartilage tumors is approximately 0.9 per 100,000 individuals. Bone and cartilage tumors have a bimodal age distribution. These tumors are more frequent in children and adolescents, and older adults. The average age at diagnosis is between 10-25 years old and 60-75 years old. Males are more commonly affected than females, with a 1.5:1 ratio.[1] Bone and cartilage tumors are slightly more common among individuals of Caucasian race.[2]

Epidemiology and Demographics

Epidemiology and Demographics

Prevalence

  • The estimated prevalence of bone and cartilage tumors is 0.2% in general population.[1]
  • The table below summarizes the frequency order of common primary malignant bone and cartilage tumors.
Primary bone malignancy Frequency (%)
Osteosarcoma 35.1
Chondrosarcoma 25.8
Ewing sarcoma 16
Chordoma 8.4
Malignant fibrous histiocytoma 5.7
Unespecifed 1.2
Others 6.4

Incidence

  • The incidence rate for all bone and cartilage malignant tumors is 0.9 per 100,000 persons per year.[1]

Age

  • The age-adjusted incidence rate of malignant bone and cartilage tumors has a bimodal distribution.[1]
  • The first peak of incidence has an average age at diagnosis between 10-25 years.
  • The second peak of incidence has an average age at diagnosis between 60-75 years.

Gender

  • Males are slightly more affected than females. The male-to-female ratio is approximately 1.5 to 1.

Race

  • Bone and cartilage tumors are slightly more common among individuals of Caucasian race.[1]
References

References

  1. 1.0 1.1 1.2 1.3 1.4 Franchi A (2012). “Epidemiology and classification of bone tumors”. Clin Cases Miner Bone Metab. 9 (2): 92–5. PMC 3476517. PMID 23087718.
  2. Tubiana-Hulin M (1991). “Incidence, prevalence and distribution of bone metastases”. Bone. 12 Suppl 1: S9–10. PMID 1954049.

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