Bornholm disease other diagnostic studies

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Arooj Naz, M.B.B.S

Overview

Diagnostic findings are limited for Bornholm disease and, because it mimics classic chest pain, extensive testing is often done to rule out cardiac conditions. Other diagnostic studied include stool, blood and throat samples. All of these have been found to contain traces of causative virus strain. In fact, they have also been found in sewage and flies. MRI can reveal changes in the muscle and fascia. Normal nerve conduction studies may be used to differentiate the disease from Guillain-Barré syndrome.

Other Diagnostic Studies

Stool Samples

Bornholm disease due to HPeV3^[1] specimens resulted in the presence of these strains in stool samples, as well as sewage and flies.^[2]

Other samples

Throat swabs^[3] and blood samples have both been found to contain causative strains within the samples.^[4]

Muscle involvement

MRI can reveal patchy distribution of thickened fascia and hyper intense muscles.^[5]

Nerve Conduction Studies

Nerve conduction studies are often normal, this may help differentiate the disease from Guillain-Barré syndrome.^[5]

References

↑ Orimo K, Hatano K, Sato N, Okabe S, Suzuki A, Mori K; et al. (2020). “Clinical Characteristics of Epidemic Myalgia Associated with Human Parechovirus Type 3 during the Summer of 2019”. Intern Med. 59 (14): 1721–1726. doi:10.2169/internalmedicine.4416-20. PMC 7434534 Check |pmc= value (help). PMID 32296005 Check |pmid= value (help).
↑ FINDLAY GM, HOWARD EM (1950). “Coxsackie viruses and Bornholm disease”. Br Med J. 1 (4664): 1233–6. doi:10.1136/bmj.1.4664.1233. PMC 2038096. PMID 15420446.
↑ FINDLAY GM, HOWARD EM (1950). “Coxsackie viruses and Bornholm disease”. Br Med J. 1 (4664): 1233–6. doi:10.1136/bmj.1.4664.1233. PMC 2038096. PMID 15420446.
↑ Orimo K, Hatano K, Sato N, Okabe S, Suzuki A, Mori K; et al. (2020). “Clinical Characteristics of Epidemic Myalgia Associated with Human Parechovirus Type 3 during the Summer of 2019”. Intern Med. 59 (14): 1721–1726. doi:10.2169/internalmedicine.4416-20. PMC 7434534 Check |pmc= value (help). PMID 32296005 Check |pmid= value (help).
↑ ^5.0 ^5.1 Orimo K, Hatano K, Sato N, Okabe S, Suzuki A, Mori K; et al. (2020). “Clinical Characteristics of Epidemic Myalgia Associated with Human Parechovirus Type 3 during the Summer of 2019”. Intern Med. 59 (14): 1721–1726. doi:10.2169/internalmedicine.4416-20. PMC 7434534 Check |pmc= value (help). PMID 32296005 Check |pmid= value (help).

Template:WH Template:WS

[pmid32296005-1] Orimo K, Hatano K, Sato N, Okabe S, Suzuki A, Mori K; et al. (2020). “Clinical Characteristics of Epidemic Myalgia Associated with Human Parechovirus Type 3 during the Summer of 2019”. Intern Med. 59 (14): 1721–1726. doi:10.2169/internalmedicine.4416-20. PMC 7434534 Check |pmc= value (help). PMID 32296005 Check |pmid= value (help).

[pmid15420446-2] FINDLAY GM, HOWARD EM (1950). “Coxsackie viruses and Bornholm disease”. Br Med J. 1 (4664): 1233–6. doi:10.1136/bmj.1.4664.1233. PMC 2038096. PMID 15420446.

[pmid154204462-3] FINDLAY GM, HOWARD EM (1950). “Coxsackie viruses and Bornholm disease”. Br Med J. 1 (4664): 1233–6. doi:10.1136/bmj.1.4664.1233. PMC 2038096. PMID 15420446.

[pmid322960052-4] Orimo K, Hatano K, Sato N, Okabe S, Suzuki A, Mori K; et al. (2020). “Clinical Characteristics of Epidemic Myalgia Associated with Human Parechovirus Type 3 during the Summer of 2019”. Intern Med. 59 (14): 1721–1726. doi:10.2169/internalmedicine.4416-20. PMC 7434534 Check |pmc= value (help). PMID 32296005 Check |pmid= value (help).

[pmid322960053-5] 5.0 ^5.1 Orimo K, Hatano K, Sato N, Okabe S, Suzuki A, Mori K; et al. (2020). “Clinical Characteristics of Epidemic Myalgia Associated with Human Parechovirus Type 3 during the Summer of 2019”. Intern Med. 59 (14): 1721–1726. doi:10.2169/internalmedicine.4416-20. PMC 7434534 Check |pmc= value (help). PMID 32296005 Check |pmid= value (help).

[1]

[2]

[3]

[4]

[5]