Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Botryomycosis
Introduction
Botryomycosis; also known as bacterial pseudomycosis is a rare chronic granulomatous bacterial infection that affects the skin, and sometimes the viscera. The disease was originally discovered by Otto Bollinger (1843-1909) in 1870, and its name was coined by Sebastiano Rivolta (1832-1893) in 1884. The name refers to its grape-like granules (Gr. botryo = grapes) and the mistakenly believed fungal etiology (Gr. mykes = fungus). In 1919 the bacterial origin of the infection was discovered. Botryomycosis has been known to affect humans, horses, cattle and swine.
Staphylococcus aureus is usually the organism that causes the infection, however it can also be caused by Pseudomonas aeruginosa or several other species of bacteria. The anatomic structure of its lesion is similar to that of actinomycosis and mycetoma, and its granules resemble the sulfur granules of actinomycosis.
There are only a handful of documented cases of botryomycosis in humans, and its pathogenesis is not completely understood. However, it is usually described in individuals with impaired immunity, or with an underlying disease such as diabetes mellitus, cystic fibrosis or HIV infection.