
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Brain Stem Gliomas historical perspective
Introduction
Overview
Overview
In the era preceding modern imaging, all brainstem gliomas were regarded as a solitary pathological entity with poor prognosis.[1] In the late 1960s, Matson suggested that all brainstem tumors were malignant and were deemed inoperable regardless of their histopathological characteristics or location. [2]This assertion was questioned shortly thereafter by Pool, who was one of the first to report tumor resection in the brainstem, which in the case described was inside the aqueduct. [3] In 1980, Hoffman et. al [4] described the dorsally exophytic group of brainstem gliomas as a distinct subgroup, and reported that these lesions were surgically curable with aggressive resection. Over the past 3 decades, the treatment of brainstem gliomas has notably progressed as a result of the gradual advancements in microsurgical techniques, sophisticated imaging technology and, most importantly, the availability of MRI. These modalities have revealed that brainstem gliomas are a heterogeneous group of tumors. [5]
References
References
- ↑ Alaqeel AM, Sabbagh AJ (2014). “Pediatric brainstem tumors. Classifications, investigations, and growth patterns”. Neurosciences (Riyadh). 19 (2): 93–9. PMID 24739404.
- ↑ Matson DD. Tumors of the posterior fossa. In: Matson DD, Ingraham FD, editors. Neurosurgery of Infancy and Childhood.2nd ed. Springfield (IL): Charles C. Thomas; 1969. p. 469-477
- ↑ Pool JL (1968). “Gliomas in the region of the brain stem”. J Neurosurg. 29 (2): 164–7. doi:10.3171/jns.1968.29.2.0164. PMID 5673314.
- ↑ Hoffman HJ, Becker L, Craven MA (1980). “A clinically and pathologically distinct group of benign brain stem gliomas”. Neurosurgery. 7 (3): 243–8. doi:10.1227/00006123-198009000-00007. PMID 7207742.
- ↑ Epstein F, Wisoff JH (1988). “Intrinsic brainstem tumors in childhood: surgical indications”. J Neurooncol. 6 (4): 309–17. PMID 3221258.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Umair Hamid, M.D[2]
