Brodie abscess historical perspective

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Abdulkerim Yassin, M.B.B.S [2]

Overview

Brodie abscess is first described by a British surgeon, sir Benjamin Brodie, in 1832. Wiles reported Brodie abscesses as a specific form of osteomyelitis in 1951. Harris and Kirkaldy-Willis (1965) were the first to describe primary subacute osteomyelitis and present a radiograph diagnosing the condition.

Historical Perspectives

Brodie abscess is first described by a British surgeon, sir Benjamin Brodie, in 1832. He severed the leg of a patient who had pain which was difficult to treat for a number of years. On examination of the amputated limb, Brodie found a cavity the size of a walnut filled with dark colored pus. The bone immediately surrounding the cavity was whiter and harder than the surrounding bone. The inner surface of the cavity appeared to be vascular. Since then, low-grade pyogenic abscesses of the bone have frequently been referred to as Brodie’s abscesses (Brodie 1832).
Wiles reported Brodie abscesses as a specific form of osteomyelitis in 1951. Harris and Kirkaldy-Willis (1965) were the first to describe primary subacute osteomyelitis and present a radiograph diagnosing the condition. ^[1]

References

↑ Halaris AE, Belendiuk KT, Freedman DX, Chow YW, Pietranico R, Mukerji A (October 1975). “Antidepressant drugs affect dopamine uptake”. Biochem Pharmacol. 24 (20): 1896–7. doi:10.1016/0006-2952(75)90412-8. PMID 19.

Overview