Bronchial atresia
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Bronchial atresia is a disorder in which a segmental bronchus fails to connect with or communicate with the more central airways. [1] [2] [3] [4] [5]
References
- ↑ Cohen AM, Solomon EH, Alfidi RJ. Computed tomography in bronchial atresia. American Journal of Roentgenology, 1980;135:1097-99.
- ↑ Rappaport DC, Herman SJ, Weisbrod GL. Congenital bronchopulmonary diseases in adults: CT findings. American Journal of Roetgenology, 1994;162: 1295-99.
- ↑ Kinsella D, Sissons G, Williams MP. The radiological imaging of bronchial atresia.British Journal of Radiology 1992;65:681-85.
- ↑ Shady K, Siegel MJ, Glazer HS. CT of focal pulmonary masses in childhood. Radiographics, 1992;12:505-514.
- ↑ Kuhn C, Kuhn JP. Coexistence of bronchial atresia and bronchogenic cyst: Diagnostic criteria and embryologic considerations. Pediatric Radiology 1992;22:568-70.
Historical Perspective
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References
Pathophysiology
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Bronchial atresia occurs when the segmental bronchus fails to connect with or communicate with the more central airways. The underlying pathophysiology is unclear and contested amongst researchers.
Pathophysiology
The underlying basis of the disorder is not clear. It has been hypothesized to be the result of a vascular injury to the lung at approximately 15 to 16 weeks gestation. An alternate hypothesis is that the disorder occurs secondary to separation of the bronchial bud during the 5th to 6th week of gestation. Pulmonary sequestration and bronchogenic cysts also form during this early period of fetal development and may share an underlying pahtophysiology.
The most common anatomic locations include the following:
- The apical posterior segment of the left upper lobe
- The left lower lobe
- The right middle lobe
References
Causes
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References
Differentiating Bronchial atresia from other Diseases
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References
Epidemiology and Demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Epidemiology and Demographics
Gender
Females outnumber males 2:1.
References
Risk Factors
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References
Natural History, Complications and Prognosis
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References
Diagnosis
Diagnosis
History and Symptoms | Physical Examination | Laboratory Findings | Chest X Ray | CT | MRI | Ultrasound | Other Imaging Findings | Other Diagnostic Studies
Treatment
Treatment
Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies
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