Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Budipine
Introduction
Overview
Overview
Budipine is an antiparkinson agent.
Its mechanism of action is not well characterized.[2] It is believed to be an NMDA receptor antagonist,[3] however, promoting the synthesis of dopamine.[4]
Because it provides additional benefits relative to existing treatments, it probably does not precisely mimic the mechanism of an existing known treatment.[5]
References
References
- ↑ Martndale: The Complete Drug Reference, 35th Ed.
- ↑ Reichmann H (October 2006). “Budipine in Parkinson’s tremor”. J. Neurol. Sci. 248 (1–2): 53–5. doi:10.1016/j.jns.2006.05.039. PMID 16784759.
- ↑ J. Kornhuber, B. Herr, J. Thome, P. Riederer. “The antiparkinsonian drug budipine binds to NMDA and sigma receptors in postmortem human brain tissue”. J.Neural Transm.Suppl. 46:127-133, 1995. PMID 8821048
- ↑ “umm.edu”.
- ↑ Przuntek H, Bittkau S, Bliesath H; et al. (May 2002). “Budipine provides additional benefit in patients with Parkinson disease receiving a stable optimum dopaminergic drug regimen”. Arch. Neurol. 59 (5): 803–6. doi:10.1001/archneur.59.5.803. PMID 12020263.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]