Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
CACNB3
Introduction
Voltage-dependent L-type calcium channel subunit beta-3 is a protein that in humans is encoded by the CACNB3 gene.[1][2]
References
References
- ↑ Collin T, Lory P, Taviaux S, Courtieu C, Guilbault P, Berta P, Nargeot J (Apr 1994). “Cloning, chromosomal location and functional expression of the human voltage-dependent calcium-channel beta 3 subunit”. Eur J Biochem. 220 (1): 257–62. doi:10.1111/j.1432-1033.1994.tb18621.x. PMID 8119293.
- ↑ “Entrez Gene: CACNB3 calcium channel, voltage-dependent, beta 3 subunit”.
Further reading
Further reading
- Yamada Y, Masuda K, Li Q, et al. (1995). “The structures of the human calcium channel alpha 1 subunit (CACNL1A2) and beta subunit (CACNLB3) genes”. Genomics. 27 (2): 312–9. doi:10.1006/geno.1995.1048. PMID 7557998.
- Rosenfeld MR, Wong E, Dalmau J, et al. (1993). “Cloning and characterization of a Lambert-Eaton myasthenic syndrome antigen”. Ann. Neurol. 33 (1): 113–20. doi:10.1002/ana.410330126. PMID 8494331.
- Murakami M, Wissenbach U, Flockerzi V (1996). “Gene structure of the murine calcium channel beta3 subunit, cDNA and characterization of alternative splicing and transcription products”. Eur. J. Biochem. 236 (1): 138–43. doi:10.1111/j.1432-1033.1996.t01-1-00138.x. PMID 8617257.
- Scott VE, De Waard M, Liu H, et al. (1996). “Beta subunit heterogeneity in N-type Ca2+ channels”. J. Biol. Chem. 271 (6): 3207–12. doi:10.1074/jbc.271.6.3207. PMID 8621722.
- Bell DC, Butcher AJ, Berrow NS, et al. (2001). “Biophysical properties, pharmacology, and modulation of human, neuronal L-type (alpha(1D), Ca(V)1.3) voltage-dependent calcium currents”. J. Neurophysiol. 85 (2): 816–27. PMID 11160515.
- Colecraft HM, Alseikhan B, Takahashi SX, et al. (2002). “Novel functional properties of Ca(2+) channel beta subunits revealed by their expression in adult rat heart cells”. J. Physiol. 541 (Pt 2): 435–52. doi:10.1113/jphysiol.2002.018515. PMC 2290333. PMID 12042350.
- Murakami M, Fleischmann B, De Felipe C, et al. (2002). “Pain perception in mice lacking the beta3 subunit of voltage-activated calcium channels”. J. Biol. Chem. 277 (43): 40342–51. doi:10.1074/jbc.M203425200. PMID 12161429.
- Qin N, Yagel S, Momplaisir ML, et al. (2002). “Molecular cloning and characterization of the human voltage-gated calcium channel alpha(2)delta-4 subunit”. Mol. Pharmacol. 62 (3): 485–96. doi:10.1124/mol.62.3.485. PMID 12181424.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). “Complete sequencing and characterization of 21,243 full-length human cDNAs”. Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Chen YH, Li MH, Zhang Y, et al. (2004). “Structural basis of the alpha1-beta subunit interaction of voltage-gated Ca2+ channels”. Nature. 429 (6992): 675–80. doi:10.1038/nature02641. PMID 15170217.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)”. Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Vendel AC, Terry MD, Striegel AR, et al. (2006). “Alternative splicing of the voltage-gated Ca2+ channel beta4 subunit creates a uniquely folded N-terminal protein binding domain with cell-specific expression in the cerebellar cortex”. J. Neurosci. 26 (10): 2635–44. doi:10.1523/JNEUROSCI.0067-06.2006. PMID 16525042.
External links
External links
- CACNB3+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
- Human CACNB3 genome location and CACNB3 gene details page in the UCSC Genome Browser.