Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
COP1
Introduction
For the membrane coated vesicle used in transport, see here.
Fagol Caspase recruitment domain-containing protein 16 is an enzyme that in humans is encoded by the CARD16 gene.[1][2][3]
References
References
- ↑ Lee SH, Stehlik C, Reed JC (Sep 2001). “Cop, a caspase recruitment domain-containing protein and inhibitor of caspase-1 activation processing”. J Biol Chem. 276 (37): 34495–500. doi:10.1074/jbc.M101415200. PMID 11432859.
- ↑ Druilhe A, Srinivasula SM, Razmara M, Ahmad M, Alnemri ES (Sep 2001). “Regulation of IL-1beta generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins”. Cell Death Differ. 8 (6): 649–57. doi:10.1038/sj.cdd.4400881. PMID 11536016.
- ↑ “Entrez Gene: COP1 caspase-1 dominant-negative inhibitor pseudo-ICE”.
External links
External links
- Human CARD16 genome location and CARD16 gene details page in the UCSC Genome Browser.
Further reading
Further reading
- Wang X, Narayanan M, Bruey JM, et al. (2006). “Protective role of Cop in Rip2/caspase-1/caspase-4-mediated HeLa cell death”. Biochim. Biophys. Acta. 1762 (8): 742–54. doi:10.1016/j.bbadis.2006.06.015. PMID 16920334.
- Wang X, Wang H, Figueroa BE, et al. (2006). “Dysregulation of receptor interacting protein-2 and caspase recruitment domain only protein mediates aberrant caspase-1 activation in Huntington’s disease”. J. Neurosci. 25 (50): 11645–54. doi:10.1523/JNEUROSCI.4181-05.2005. PMID 16354923.
- Lamkanfi M, Denecker G, Kalai M, et al. (2005). “INCA, a novel human caspase recruitment domain protein that inhibits interleukin-1beta generation”. J. Biol. Chem. 279 (50): 51729–38. doi:10.1074/jbc.M407891200. PMID 15383541.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). “Complete sequencing and characterization of 21,243 full-length human cDNAs”. Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Razmara M, Srinivasula SM, Wang L, et al. (2002). “CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis”. J. Biol. Chem. 277 (16): 13952–8. doi:10.1074/jbc.M107811200. PMID 11821383.