Calciphylaxis causes

• The cause is not known. It does not seem to be an immune type reaction. In other words, calciphylaxis is not only a hypersensitivity reaction (= allergic reaction) leading to sudden local calcification. Clearly, additional factors are involved in calciphylaxis. It possibly could be described as calcific uraemic arteriolopathy.
• Secondary hyperparathyroidism may sometimes cause calciphylaxis.^[1]

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