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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Cancer of unknown primary origin history and symptoms

Introduction

Overview

Overview

The majority of patients with cancer of unknown primary origin are asymptomatic.

History and Symptoms

History and Symptoms

The majority of patients with cancer of unknown primary origin are asymptomatic.[1]

The hallmark of CUP is determined by the specific metastatic sites involved, which are usually more than one at time of diagnosis.

Patients often present with signs and symptoms related to the sites involved including the liver, lungs, lymph nodes, and bones.

Common Symptoms

Common symptoms of cancer of unknown primary origin may include the following:[1]

Less Common Symptoms

Less common symptoms of cancer of unknown primary origin may include the following:[1]

References

References

  1. ↑ 1.0 1.1 1.2 Varadhachary GR (2007). “Carcinoma of unknown primary origin”. Gastrointest Cancer Res. 1 (6): 229–35. PMC 2631214. PMID 19262901.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: ; Roukoz A. Karam, M.D.[2]