Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Capillary leak syndrome future or investigational therapies
Introduction
Overview
Overview
The relationship between Capillary leak syndrome and post-episodic levels of monoclonal IgG are of interest and continue to be studied. In one out of five patients, a monoclonal IgG gammopathy has been found.
Future or Investigational therapies
Future or Investigational therapies
After an attack, various substances were measured in the body including products derived the coagulation pathway, complement pathway, bradykinin generation, prostaglandins and histamine metabolism. Although these products were all in within normal limits, affected individuals were continuously found to have a monoclonal IgG gammopathy. Studies continue to be done to understand the relationship between monoclonal IgG gammopathy and Capillary leak syndrome.[1]
References
References
- ↑ Atkinson JP, Waldmann TA, Stein SF, Gelfand JA, Macdonald WJ, Heck LW; et al. (1977). “Systemic capillary leak syndrome and monoclonal IgG gammopathy; studies in a sixth patient and a review of the literature”. Medicine (Baltimore). 56 (3): 225–39. doi:10.1097/00005792-197705000-00004. PMID 870792.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [[1]]; Associate Editor(s)-In-Chief: M. Hassan, M.B.B.S