Capillary leak syndrome history and symptoms

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: M. Hassan, M.B.B.S

Overview

History and Symptoms

The symptoms of systemic capillary leak syndrome may be categorized as prodromal and acute attack symptoms. Flulike illness and myalgias were characteristic of crisis in most patients, however, the prodromata varied significantly. Most patient reported exhaustion, fatigue, and light-headedness at the onset of an attack.

Below are the tables that depict symptoms characteristic of prodromal and acute phase of capillary leak syndrome.^[1]

Symptoms that are seen during the prodromal phase of capillary leak syndrome
Prodromal Symptoms
Fatigue Presyncope/light-headedness Flulike illness Myalgias Scratchy throat Change in mood Reduced urinary frequency Dark urine

Symptoms present during an acute attack of capillary leak syndrome
Acute attack Symptoms
Pain (generalized body aches or localized pain, excluding cephalgia) Nausea/Vomiting Fever Flushing Jaw claudication Dyspnea Dysphagia Loss of consciousness Periorbital edema/facial swelling Weight gain Increased thirst Diaphoresis Hoarseness Headaches Rhinorrhea Rash Arthralgia Lacrimation Pruritus

References

↑ Kapoor P, Greipp PT, Schaefer EW, Mandrekar SJ, Kamal AH, Gonzalez-Paz NC; et al. (2010). “Idiopathic systemic capillary leak syndrome (Clarkson’s disease): the Mayo clinic experience”. Mayo Clin Proc. 85 (10): 905–12. doi:10.4065/mcp.2010.0159. PMC 2947962. PMID 20634497.

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[pmid20634497-1] Kapoor P, Greipp PT, Schaefer EW, Mandrekar SJ, Kamal AH, Gonzalez-Paz NC; et al. (2010). “Idiopathic systemic capillary leak syndrome (Clarkson’s disease): the Mayo clinic experience”. Mayo Clin Proc. 85 (10): 905–12. doi:10.4065/mcp.2010.0159. PMC 2947962. PMID 20634497.

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Capillary leak syndrome history and symptoms

Overview

History and Symptoms

References

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