Caplans syndrome epidemiology and demographics

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sharmi Biswas, M.B.B.S

Overview

The incidence of Caplan syndrome is 1 in 100,000 people but it is decreasing due to the reduction of exposure to coal, silica, and asbestos. Silica exposure has the most prevalence of Caplan syndrome.

Epidemiology and Demographics

Incidence

Caplan syndrome is very rare in the United States. Incidence is currently 1 in 100,000 people but is likely to fall as the coal mining industry declines.^[1]

Prevalence

The prevalence of Caplan syndrome is estimated to be very low.^[1]
Most recent study showed the prevalence of Caplan syndrome n Japan is 0.75% and in the USA it is 0.89%. No recent study on the prevalence in Europe.^[2]

case-fatality rate/Mortality rate

Mortality rate in Caplan syndrome is very low except in association with black lung caused by coal worker pneumoconiosis.^[3]

Age

Aveerage age of first radiographic appearance of Caplan syndrome is 54 years. The age range is 41 to 64 years of age. ^[4]^[5]

Race

There is no racial predilection to Caplan syndrome.

Gender

There is no study available on gender.

Region

The majority of Caplan syndrome cases are reported 0.75% in Japan and 1.5% in the United States.^[6]

References

↑ ^1.0 ^1.1 “StatPearls”. 2021. PMID 29763061. PMID: 29763061. Check |pmid= value (help).
↑ Benedek, Thomas G. (1973). “Rheumatoid pneumoconiosis”. The American Journal of Medicine. 55 (4): 515–524. doi:10.1016/0002-9343(73)90209-X. ISSN 0002-9343.
↑ Shaw, Megan; Collins, Bridget F.; Ho, Lawrence A.; Raghu, Ganesh (2015). “Rheumatoid arthritis-associated lung disease”. European Respiratory Review. 24 (135): 1–16. doi:10.1183/09059180.00008014. ISSN 0905-9180.
↑ Lindars, D. C.; Davies, D. (1967). “Rheumatoid pneumoconiosis: A study in colliery populations in the East Midlands coalfield”. Thorax. 22 (6): 525–532. doi:10.1136/thx.22.6.525. ISSN 0040-6376.
↑ Alaya, Zeineb; Braham, Mouna; Aissa, Sana; Kalboussi, Houda; Bouajina, Elyès (2018). “A case of Caplan syndrome in a recently diagnosed patient with silicosis: A case report”. Radiology Case Reports. 13 (3): 663–666. doi:10.1016/j.radcr.2018.03.004. ISSN 1930-0433.
↑ “Rheumatoid Pneumoconiosis: A Comparative Study of Autopsy Cases between Japan and North America”. The Annals of Occupational Hygiene. 2002. doi:10.1093/annhyg/46.suppl_1.265. ISSN 1475-3162.

[pmidPMID:_29763061.-1] 1.0 ^1.1 “StatPearls”. 2021. PMID 29763061. PMID: 29763061. Check |pmid= value (help).

[Benedek1973-2] Benedek, Thomas G. (1973). “Rheumatoid pneumoconiosis”. The American Journal of Medicine. 55 (4): 515–524. doi:10.1016/0002-9343(73)90209-X. ISSN 0002-9343.

[ShawCollins2015-3] Shaw, Megan; Collins, Bridget F.; Ho, Lawrence A.; Raghu, Ganesh (2015). “Rheumatoid arthritis-associated lung disease”. European Respiratory Review. 24 (135): 1–16. doi:10.1183/09059180.00008014. ISSN 0905-9180.

[LindarsDavies1967-4] Lindars, D. C.; Davies, D. (1967). “Rheumatoid pneumoconiosis: A study in colliery populations in the East Midlands coalfield”. Thorax. 22 (6): 525–532. doi:10.1136/thx.22.6.525. ISSN 0040-6376.

[AlayaBraham2018-5] Alaya, Zeineb; Braham, Mouna; Aissa, Sana; Kalboussi, Houda; Bouajina, Elyès (2018). “A case of Caplan syndrome in a recently diagnosed patient with silicosis: A case report”. Radiology Case Reports. 13 (3): 663–666. doi:10.1016/j.radcr.2018.03.004. ISSN 1930-0433.

[6] “Rheumatoid Pneumoconiosis: A Comparative Study of Autopsy Cases between Japan and North America”. The Annals of Occupational Hygiene. 2002. doi:10.1093/annhyg/46.suppl_1.265. ISSN 1475-3162.

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