The incidence of carcinoma of the penis is approximately 1 per 100,000 males in the United States. The majority of cases are reported in less developed areas. The incidence of carcinoma of the penis increases with age; the median age at diagnosis is 60 years.

• Penile cancer is a malignancy that is rare in the Western Hemisphere ^{[1] [2]}
• The incidence of carcinoma of the penis is approximately 1 per 100,000 males in the United States
• Penile cancer accounts for 0.4–0.6% of malignant diagnoses in the USA and Europe, and is responsible for 0.1% of cancer deaths
• The incidence is significantly higher in developing countries where penile cancer constitutes a significant public health hazard
• Two pathways have been proposed for penile cancer development—one related to HPV infection and the other related to phimosis and/or chronic inflammation

The incidence of carcinoma of the penis increases with age; the median age at diagnosis is 60 years.^[3][4]

Carcinoma of the penis usually affects individuals of the white, African American, and Hispanic race. Asian males are less likely to develop carcinoma of the penis.^[3]

The majority of carcinoma of the penis cases are reported in less developed areas, such as Africa, Asia, and South America.^[5]