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Carpal tunnel syndrome laboratory findings

Introduction

  • Nonspecific:

No direct laboratory marker confirms CTS.

  • Supportive / Etiologic evaluation:
    • Thyroid function tests: Hypothyroidism is a known risk factor.
    • Fasting glucose / HbA1c: To evaluate for diabetes mellitus, which is associated with peripheral neuropathy and CTS.
    • Vitamin B12 levels: To rule out concomitant neuropathy.
    • Rheumatologic markers (ESR, CRP, ANA, RF): May be obtained if inflammatory arthritis (e.g., rheumatoid arthritis, lupus) is suspected.
    • Uric acid: Considered in suspected gout-related CTS.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Dheeraj Makkar, M.D.[2]