
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Case series
Introduction
A case series (also known as a clinical series) is a medical research study that tracks patients with a known exposure given similar treatment[1] or examines their medical records for exposure and outcome.
A case series can be retrospective or prospective and usually involves a smaller number of patients than more powerful case-control studies or randomized controlled trials.
A case series is a type of observational study. Case series may be consecutive[2] or non-consecutive,[3] depending on whether all cases presenting to the reporting authors over a period of time were included, or only a selection.
Case series may be confounded by selection bias, which limits statements on the causality of correlations observed.
