Castleman's disease causes

• About 50% of Multicentric Castleman’s disease (MCD) is caused by Kaposi’s sarcoma-associated herpesvirus (KSHV), a gammaherpesvirus that is also the cause of Kaposi’s sarcoma and primary effusion lymphoma, while the remainder of MCD are of unknown cause.
• The form of MCD most closely associated with KSHV is the plasmacytic form of Castleman’s disease while another pathologic form, the hyaline-vascular form, is generally negative for this virus.

de:Morbus Castleman

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