Castleman's disease classification

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]

Overview

Classification

Two types of classifications exist for Castleman’s disease. They are:

Clinical and Radiologic classification:
- Unicentric – single lymph node is involved, most commonly in the mediastinum or the mesentery.
- Multicentric – wide spread involvement of lymph nodes and also liver and spleen in some cases

Histopathologic classification:
- Hyaline vascular
- Plasmacytic
- Mixed cellularity – has features of both hyaline vascular type and plasmacytic type.

References

Overview