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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Castleman's disease other diagnostic studies

Introduction

Overview

Overview

Biopsy

Biopsy

  • Lymph node biopsy is used as a differentiating tool in the diagnosis of Castleman’s disease. It is used to differentiate Castleman’s from lymphoma.
  • Variants of Castleman’s disease can also be differentiated using biopsy.
Micrograph of Castleman’s disease, hyaline vascular variant, exhibiting the characteristically expanded mantle zone and a radially penetrating sclerotic blood vessel (“lollipop” sign). H&E stain.
Intermediate magnification micrograph of Castleman disease showing the characteristic expansion of the mantle zone, known as “onion skinning”. H&E stain.
References

References

de:Morbus Castleman

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]