Health Dictionary
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Catecholaminergic polymorphic ventricular tachycardia classification
Introduction
Overview
Overview
Catecholaminergic polymorphic ventricular tachycardia can be classified based upon the underlying pathogenic mutation.
Classification
Classification
CPVT may be classified based upon the underlying pathogenic mutation into the following subtypes:[1]
| Type | OMIM | Gene | Protein | Mode of inheritance | Locus |
|---|---|---|---|---|---|
| CPVT1 | 604772 | RyR2 | Ryanodine receptor 2 | Autosomal dominant | 1q42.1-q43 |
| CPVT2 | 611938 | CASQ2 | Calsequestrin 2 | Autosomal recessive | 1p13.3-p11 |
| CPVT3 | 614021 | Unknown | – | Autosomal recessive | 7p14–p22 |
| CPVT4 | 614916 | CALM1 | Calmodulin 1 | Autosomal dominant | 14q32.11 |
| CPVT5 | 615441 | TRDN | Triadin | Autosomal recessive | 6q22.31 |
References
References
- ↑ Sumitomo, Naokata (2016). “Current topics in catecholaminergic polymorphic ventricular tachycardia”. Journal of Arrhythmia. 32 (5): 344–351. doi:10.1016/j.joa.2015.09.008. ISSN 1880-4276.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mounika Reddy Vadiyala, M.B.B.S.[2]