Health Dictionary
Reliable, easy-to-read patient information on common medical conditions β written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Cavum septum pellucidum
Introduction
Overview
Overview
CSP is bounded anteriorly by the genu of the corpus callosum; superiorly by the body of the corpus callosum; posteriorly by the anterior limb and pillars of the fornix; inferiorly by the anterior commissure and the rostrum of the corpus callosum; and laterally by the leaflets of the septum pellucidum [1].
Classification
Classification
The most common type of CSP is noncommunicating, that is, it does not connect to the brain’s ventricular system. Because of this lack of communication, the erstwhile term for CSP, the “fifth ventricle,” is not anatomically correct and its use has fallen out of favor in recent years.
CSP is present in 100% of fetuses, but over 85% of them fuse by 3β6 months of age [2]. It has been loosely associated with schizophrenia, post-traumatic stress disorder, and chronic brain trauma [3] [4] [5].
References
References
- β Born C, Meisenzahl E, Frodl T, Pfluger T, Reiser M, MΓΆller H, Leinsinger G (2004). “The septum pellucidum and its variants. An MRI study”. European archives of psychiatry and clinical neuroscience. 254 (5): 295β302. PMIDΒ 15365704.
- β Farruggia S, Babcock D (1981). “The cavum septi pellucidi: its appearance and incidence with cranial ultrasonography in infancy”. Radiology. 139 (1): 147β50. PMIDΒ 7208915.
- β May F, Chen Q, Gilbertson M, Shenton M, Pitman R (2004). “Cavum septum pellucidum in monozygotic twins discordant for combat exposure: relationship to posttraumatic stress disorder”. Biol. Psychiatry. 55 (6): 656β8. PMIDΒ 15013837.
- β Galarza M, Merlo A, Ingratta A, Albanese E, Albanese A (2004). “Cavum septum pellucidum and its increased prevalence in schizophrenia: a neuroembryological classification”. The Journal of neuropsychiatry and clinical neurosciences. 16 (1): 41β6. PMIDΒ 14990758.
- β Zhang L, Ravdin L, Relkin N, Zimmerman R, Jordan B, Lathan W, UluΔ A (2003). “Increased diffusion in the brain of professional boxers: a preclinical sign of traumatic brain injury?”. AJNR. American journal of neuroradiology. 24 (1): 52β7. PMIDΒ 12533327.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]