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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Central pontine myelinolysis MRI

Introduction

Overview

Overview

Brain and spinal cord MRIs may be helpful in the diagnosis of Central pontine myelinolysis. Findings on MRI diagnostic of Central pontine myelinolysis include: Symmetric signal intensity abnormality in the central pons at T2-weighted and FLAIR imaging which may progress to classic hyperintense “trident-shaped” central pontine abnormality, with sparing of the ventrolateral pons and corticospinal tracts, decreased T1 signal intensity, fluid attenuated inversion recovery (FLAIR) hyperintense lesion in the pons and intramedullary central T2 hyperintensity at axial T2W of spinal cord and sagittal T2W of thoracic spinal cord.

MRI

MRI

Brain and spinal cord MRIs may be helpful in the diagnosis of Central pontine myelinolysis. Findings on MRI diagnostic of Central pontine myelinolysis include:[1][2]

  • Symmetric signal intensity abnormality in the central pons at T2-weighted and FLAIR imaging
    • This may progress to classic hyperintense “trident-shaped” central pontine abnormality, with sparing of the ventrolateral pons and corticospinal tracts
  • Decreased T1 signal intensity
  • Fluid attenuated inversion recovery (FLAIR) hyperintense lesion in the pons
  • Intramedullary central T2 hyperintensity at axial T2W of spinal cord and sagittal T2W of thoracic spinal cord
References

References

  1. ↑ Ruzek KA, Campeau NG, Miller GM (2004). “Early diagnosis of central pontine myelinolysis with diffusion-weighted imaging”. AJNR Am J Neuroradiol. 25 (2): 210–3. PMID 14970019.
  2. ↑ Jacob S, Gupta H, Nikolic D, Gundogdu B, Ong S (2014). “Central pontine and extrapontine myelinolysis: the great masquerader-an autopsy case report”. Case Rep Neurol Med. 2014: 745347. doi:10.1155/2014/745347. PMC 3970353. PMID 24716023.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]