Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Central pontine myelinolysis epidemiology and demographics
Introduction
Overview
Overview
The prevalence of central pontine myelinolysis is approximately 250–500 per 100,000 in the general population. Among hospitalized patients in the ICU the incidence of central pontine myelinolysis is approximately 2500 per 100,000 patients. Among patients undergoing liver transplantation the incidence of central pontine myelinolysis is approximately 10,000 per 100,000 patients. The case-mortality rate of central pontine myelinolysis is approximately 12%. Patients of all age groups may develop central pontine myelinolysis but the incidence of central pontine myelinolysis increases with age. There is no racial predilection to central pontine myelinolysis. Central pontine myelinolysis affects men and women equally. There is no regional predilection to central pontine myelinolysis.
Epidemiology and Demographics
Epidemiology and Demographics
Incidence and prevalence
- The prevalence of central pontine myelinolysis is approximately 250–500 per 100,000 in the general population.[1]
- Among hospitalized patients in the ICU the incidence of central pontine myelinolysis is approximately 2500 per 100,000 patients.[2][1]
- Among patients undergoing liver transplantation the incidence of central pontine myelinolysis is approximately 10,000 per 100,000 patients.[2][3][1]
Mortality rate
- The case-mortality rate of central pontine myelinolysis is approximately 12%.[1]
Age
- Patients of all age groups may develop central pontine myelinolysis but the incidence of central pontine myelinolysis increases with age.
Race
- There is no racial predilection to central pontine myelinolysis.
Gender
- Central pontine myelinolysis affects men and women equally.[4]
Region
- There is no regional predilection to central pontine myelinolysis.
References
References
- ↑ 1.0 1.1 1.2 1.3 Rao PB, Azim A, Singh N, Baronia AK, Kumar A, Poddar B (2015). “Osmotic demyelination syndrome in Intensive Care Unit”. Indian J Crit Care Med. 19 (3): 166–9. doi:10.4103/0972-5229.152760. PMC 4366916. PMID 25810613.
- ↑ 2.0 2.1 Menger H, Jörg J (1999). “Outcome of central pontine and extrapontine myelinolysis (n = 44)”. J Neurol. 246 (8): 700–5. PMID 10460448.
- ↑ Lampl C, Yazdi K (2002). “Central pontine myelinolysis”. Eur Neurol. 47 (1): 3–10. doi:10.1159/000047939. PMID 11803185.
- ↑ Bansal LR, Zinkus T (2019). “Osmotic Demyelination Syndrome in Children”. Pediatr Neurol. 97: 12–17. doi:10.1016/j.pediatrneurol.2019.03.018. PMID 31128892.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]