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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Central pontine myelinolysis historical perspective

Introduction

Overview

Overview

Central pontine myelinolysis was first discovered by Raymond Delacy Adams, an an American neurologist, in 1959. Raymond Delacy Adams and colleagues observed a rapidly evolving quadriplegia and pseudobulbar palsy in a young alcoholic man whose postmortem examination showed a large, symmetrical, essentially demyelinative lesion occupying the greater part of the base of the pons In 1950.

Historical Perspective

Historical Perspective

Discovery

  • Central pontine myelinolysis was first discovered by Raymond Delacy Adams, an an American neurologist, in 1959.[1][2][3][4]
  • Raymond Delacy Adams and colleagues observed a rapidly evolving quadriplegia and pseudobulbar palsy in a young alcoholic man whose postmortem examination showed a large, symmetrical, essentially demyelinative lesion occupying the greater part of the base of the pons In 1950.[2][3][4]
References

References

  1. ↑ Fisher CM (2010). “Dr. Raymond Delacy Adams (1911-2008): an appreciation”. Neurologist. 16 (3): 141–2. doi:10.1097/NRL.0b013e3181c9280a. PMID 20445423.
  2. ↑ 2.0 2.1 ADAMS RD, VICTOR M, MANCALL EL (1959). “Central pontine myelinolysis: a hitherto undescribed disease occurring in alcoholic and malnourished patients”. AMA Arch Neurol Psychiatry. 81 (2): 154–72. PMID 13616772.
  3. ↑ 3.0 3.1 Mohammed AS, Boddu P, Yazdani DF (2016). “Clinical Evolution of Central Pontine Myelinolysis in a Patient with Alcohol Withdrawal: A Blurred Clinical Horizon”. Case Rep Med. 2016: 6065259. doi:10.1155/2016/6065259. PMC 5004014. PMID 27610136.
  4. ↑ 4.0 4.1 Kumar S, Fowler M, Gonzalez-Toledo E, Jaffe SL (2006). “Central pontine myelinolysis, an update”. Neurol Res. 28 (3): 360–6. doi:10.1179/016164106X110346. PMID 16687066.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: , Mohamadmostafa Jahansouz M.D.[2]