Cerebral venous sinus thrombosis natural history

Common complications of cerebral venous thrombosis include neurological deficits, coma, and death.

• The symptoms of cerebral venous thrombosis(CVT) usually develop in the first decade of life, and start with symptoms such as headache, seizures, neurological deficits, visual impairment, decreased level of consciousness. ^[1][2]

• 15% of patients with CVT may progress to develop residual epilepsy, cognitive impairment, recurrent CVT or systemic thromboembolism.

• Common complications of cerebral venous thrombosis (CVT) include:
  • Hydrocephalus^[2][1]
  • Cognitive impairment
  • Neurological deficit
  • Residual epilepsy
  • Coma
  • Death

The prognosis of CVT is favorable than other strokes. Complete functional recovery has been reported in 75% of patients but 15% of patients die or become dependent.^[3] Study showed women has better prognosis than men. 81% of women recovered completely while only 71 % of men had so.^[4] Recurrent thrombosis is a common complication in CVT, around 6.5% per year but mostly in patients who are not on anticoagualnts.^[3]