Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Chlormezanone
Introduction
Overview
Overview
Chlormezanone (marketed under the brandname Trancopal or Fenaprim) is a drug used as an anxiolytic and a muscle relaxant. Its use was discontinued in many countries from 1996 on, due to rare but serious cases of toxic epidermal necrolysis.
Chemistry
Chemistry
References
References
- Wollina U, Hipler U, Seeling A, Oelschlager H (2005). “Investigations of interactions of chlormezanone racemate and its enantiomers on human keratinocytes and human leucoytes in vitro”. Skin Pharmacol Physiol. 18 (3): 132–138. doi:10.1159/000084910. PMID 15897685.
- Seeling A, Oelschläger H, Rothley D (2000). “Important pharmaceutical-chemical characteristics of the central muscle relaxant chlormezanone”. Pharmazie. 55 (4): 293–6. PMID 10798243.
- Oelschläger H, Klinger W, Rothley D, Seeling A, Bockhard H, Hofmann B, Machts H, Riederer H, Rackur H (1998). “[Cleavage and biotransformation of the central muscle relaxant chlormezanone]”. Pharmazie. 53 (9): 620–4. PMID 9770210.
- Gautier V, Vincon G, Demotes-Mainard F, Albin H (1990). “[Pharmacokinetics of chlormezanone in healthy volunteers] (original in French)”. Pharmazie. 45 (4): 315–9. PMID 2399514.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]