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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Chondroma causes

Introduction

Overview

Overview

The cause of chondromas has not been identified.

Causes

Causes

The cause of chondromas has not been identified. Fibroblast growth factor receptor (FGFR3) deletion may be induced multiple chondroma-like lesions, including enchondromas and osteochondromas.^[1]
However, enchondroma is believed to occur either as:
- An overgrowth of the cartilage that lines the ends of the bones
- A persistent growth of original embryonic cartilage.

References

References

↑ Zhou S, Xie Y, Tang J, Huang J, Huang Q, Xu W, Wang Z, Luo F, Wang Q, Chen H, Du X, Shen Y, Chen D, Chen L (June 2015). “FGFR3 Deficiency Causes Multiple Chondroma-like Lesions by Upregulating Hedgehog Signaling”. PLoS Genet. 11 (6): e1005214. doi:10.1371/journal.pgen.1005214. PMC 4474636. PMID 26091072.

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Farima Kahe M.D. [2], Soujanya Thummathati, MBBS [3]