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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Chondrosarcoma surgery

Introduction

Overview

Overview

Surgery is the mainstay of treatment for chondrosarcoma. Adjunctive chemotherapy and radiation may be required. Recurrence rate depends on the grade of chondrosarcoma.

Surgery

Surgery

Intra-Lesional Curettage

Indications

Wide Surgical Excision

Indications

  • Grade 2 or 3 chondrosarcoma anywhere in the body.
  • Grade 1 chondrosarcoma in pelvis.

Wide Surgical Excision Combined with Multi-Agent Chemotherapy

Indications

  • Mesenchymal chondrosarcoma.

Limb-salvage through Pelvic Resection with or without Reconstruction

Indications

  • Dedifferentiated chondrosarcoma involving the pelvis.[6]

Limb-sacrifice with Hindquarter Amputation

Indications

  • Dedifferentiated chondrosarcoma involving the pelvis[6]

Recurrence Rate

Grade 1 chondrosarcoma

Grade 2 chondrosarcoma

  • The recurrence rate varies depending on resection margins.

Grade 3 chondrosarcoma

  • The local recurrence rate is 25% and >30% chances of metastasis.
Chondrosarcoma of glenoid and scapula. Source: Case courtesy by: Dr. Rohan A. Bhimani
References

References

  1. ↑ Peabody, Terrance (2014). Orthopaedic oncology : primary and metastatic tumors of the skeletal system. Cham: Springer. ISBN 9783319073224.
  2. ↑ Czerniak, Bogdan (2016). Dorfman and Czerniak’s bone tumors. Philadelphia, PA: Elsevier/Saunders. ISBN 9780323023962.
  3. ↑ Lex JR, Evans S, Stevenson JD, Parry M, Jeys LM, Grimer RJ (2018). “Dedifferentiated chondrosarcoma of the pelvis: clinical outcomes and current treatment”. Clin Sarcoma Res. 8: 23. doi:10.1186/s13569-018-0110-1. PMC 6293503. PMID 30559960.
  4. ↑ Ozaki T, Lindner N, Hillmann A, Rödl R, Blasius S, Winkelmann W (1996). “Influence of intralesional surgery on treatment outcome of chondrosarcoma”. Cancer. 77 (7): 1292–7. doi:10.1002/(SICI)1097-0142(19960401)77:7<1292::AID-CNCR10>3.0.CO;2-X. PMID 8608505.
  5. ↑ Marco RA, Gitelis S, Brebach GT, Healey JH (2000). “Cartilage tumors: evaluation and treatment”. J Am Acad Orthop Surg. 8 (5): 292–304. PMID 11029557.
  6. ↑ 6.0 6.1 Dickey ID, Rose PS, Fuchs B, Wold LE, Okuno SH, Sim FH; et al. (2004). “Dedifferentiated chondrosarcoma: the role of chemotherapy with updated outcomes”. J Bone Joint Surg Am. 86-A (11): 2412–8. PMID 15523011.

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rohan A. Bhimani, M.B.B.S., D.N.B., M.Ch.[2]