Nocturnal angina pectoris

For patient information, click here.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]

Overview

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Please help WikiDoc by adding more content here. It’s easy! Click here to learn about editing.

Overview

Nocturnal angina is the occurrence of anginal discomfort either during the initial few hours of sleep or during the early morning hours. It is speculated that discomfort caused during the first hour of sleep is due to increased venous return, whereas the discomfort caused during the early morning hours is due to increased vascular tone.

Treatment

Medical Therapy

The treatment of nocturnal angina pectoris is same as the chronic stable angina. If increased coronary vascular tone is felt to be the underlying mechanism, the calcium channel blockade may be of benefit.

References

Template:WH Template:WS

Pathophysiology

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Please help WikiDoc by adding more content here. It’s easy! Click here to learn about editing.

Pathophysiology

Among patients who develop nocturnal angina within one to two hours of falling asleep, the mechanism of angina in this group is likely to be an increase in venous return and hence an increased intracardiac volume, with a resulting increase in myocardial oxygen requirements.
Among patients who develop nocturnal angina in the early morning hours, increased coronary vascular tone causing a primary reduction in coronary blood flow has been postulated as the potential underlying mechanism. This is due to the diurnal increase in sympathetic activity which occurs in the early morning hours causing increased heart rate, blood pressure, and vascular tone.