Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Colon polyps differential diagnosis
Introduction
Overview
Overview
Colon polyps might present solitary or multiple. Solitary colon polyps usually have no symptoms. Colon polyps must be differentiated from other genetic diseases that cause multiple polyps, such as Peutz–Jeghers syndrome, Cowden syndrome, Bannayan–Riley–Ruvalcaba syndrome, juvenile polyposis, and McCune–Albright syndrome.
Differentiating Colon Polyps from other Diseases
Differentiating Colon Polyps from other Diseases
Colon polyps must be differentiated from the following diseases:[1][2]
- Peutz–Jeghers syndrome
- Cowden syndrome
- Cronkhite–Canada syndrome
- Bannayan–Riley–Ruvalcaba syndrome
- Juvenile polyposis
- McCune–Albright syndrome
Differential diagnosis according to polys:
| Diseases | History and Symptoms | Physical Examination | Laboratory Findings | Other Findings | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Abdominal Pain | Rectal Bleeding | Hyperpigmentation | Fatigue | Abdominal Tenderness | Hyperpigmentation | Anemia | Gene(s) | Sertoli Cell Tumors | Gastrointestinal Tumors | Cancers | ||
| Juvenile Polyposis Syndrome | + | _ | – | + | – | – | – |
|
– | _ | ||
| Cowden Syndrome | – | – | – | – | – | – | ||||||
| Carney Syndrome | – | – | – | – | – | ++ | ||||||
| Familial Adenomatous Polyposis | + | + | – | + | +/– | – | + | – |
|
|||
| Hereditary Non–Polyposis Colon Cancer | – | + | – | + | +/– | – | + | – | ||||
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References
References
- ↑ Buck, J L; Harned, R K; Lichtenstein, J E; Sobin, L H (1992). “Peutz-Jeghers syndrome”. RadioGraphics. 12 (2): 365–378. doi:10.1148/radiographics.12.2.1561426. ISSN 0271-5333.
- ↑ “Peutz-Jeghers Syndrome – GeneReviews® – NCBI Bookshelf”.
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sadaf Sharfaei M.D.[2]