Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Congenital diaphragmatic hernia risk factors
Introduction
Overview
Overview
Unlike other hernias that develop to a progressive weakening in the abdominal wall, CDH occurs due to anatomical defects leading to postero-lateral wall weakness. The use of medications and environmental exposures such as allopurinol, lithium and mycophenolate mofetil as well as phenmetrazine, thalidomide, quinine, cadmium and lead can all contribute to the development of CDH. Genetic factors such as trisomy 13, trisomy 18, trisomy 21 and turner syndrome have all been associated with an increased incidence of CDH. A family history such as a parent or sibling affected may contribute to increased risk of CDH development.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Arooj Naz, M.B.B.S