Developer site: The content shown here is test data.

MyEClinic
MyEClinic
Health Dictionary AI Health Chat Find an Online Doctor
A serene Zen garden with raked sand and smooth stones, symbolising clarity and calm

Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

Back to skin conditions

Congenital syphilis other diagnostic studies

Introduction

Overview

Overview

Pathologic examination of the placenta or umbilical cord by using specific fluorescent antitreponemal antibody staining and CSF analysis can be done.

Other Diagnostic Findings

Other Diagnostic Findings

CSF Analysis

Indications : Lumbar puncture is indicated in the following situations.[1]

  • If the infant or child has signs and symptoms of congenital Syphilis.
  • If there is no documentation of treatment for maternal infection during the period of gestation.
  • If the mother was treated within 4 weeks of delivery.
  • If the mother was inadequately treated or documentation of the treatment is incomplete.
  • A four-fold decline in titer following therapy in the mother is not documented.

CSF Findings:

  • Reactive CSF VDRL. [2]
  • CSF pleocytosis(>25 white blood cells [WBC]/microL for infants <1 month)
  • Elevated CSF protein (>150 mg/dL in term infants <1 month of age and >170 mg/dL in preterm infants <1 month of age)
References

References

  1. ↑ Phiske, MeghanaMadhukar (2014). “Current trends in congenital syphilis”. Indian Journal of Sexually Transmitted Diseases and AIDS. 35 (1): 12. doi:10.4103/0253-7184.132404. ISSN 0253-7184.
  2. ↑ Workowski KA, Bolan GA, Centers for Disease Control and Prevention (2015). “Sexually transmitted diseases treatment guidelines, 2015”. MMWR Recomm Rep. 64 (RR-03): 1–137. PMID 26042815.

Template:WikiDoc Sources

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]Aravind Kuchkuntla, M.B.B.S[3]