Creatinine increase is the characteristic finding in CIN, kidney injury occure with in minutes of exposure to contrast agents, however clinical manifestations such as oliguria or elevation of serum creatinine are generally observed within 24 to 48 hours after contrast exposure.

In most of cases, the increase in creatinine occurs within 24 to 48 hours of contrast administration, which reflect decline in GFR, the creatinine usually starts to decline within three to seven days, other laboratory manifestations may be present, including hyperkalemia, acidosis and hyperphosphatemia.^[1] Other symptoms of Acute kidney injury may be present.