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Contrast induced nephropathy history and symptoms

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]

Overview

Overview

Creatinine increase is the characteristic finding in CIN, kidney injury occure with in minutes of exposure to contrast agents, however clinical manifestations such as oliguria or elevation of serum creatinine are generally observed within 24 to 48 hours after contrast exposure.

History and Symptoms

History and Symptoms

In most of cases, the increase in creatinine occurs within 24 to 48 hours of contrast administration, which reflect decline in GFR, the creatinine usually starts to decline within three to seven days, other laboratory manifestations may be present, including hyperkalemia, acidosis and hyperphosphatemia.[1] Other symptoms of Acute kidney injury may be present.

References

References

  1. Rudnick MR, Berns JS, Cohen RM, Goldfarb S (1994). “Nephrotoxic risks of renal angiography: contrast media-associated nephrotoxicity and atheroembolism–a critical review”. Am J Kidney Dis. 24 (4): 713–27. PMID 7942832.

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