Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Corticovirus
Introduction
The Corticovirus or Corticoviridae are a family of phages that consist of a round, icosahedral, non-enveloped capsid of a diameter of 60 nm and an internal lipid membrane located between outer and inner protein shell[1]. The shells are composed of three layers which surfaces reveals a pattern with distinctive features[2], including bush-like spikes protruding from the twelve vertices[3].
Genome
Genome
The genome is not segmented, constitutes 13% of the virus’s weight and contains a single molecule of circular, supercoiled, double-stranded DNA of 9500-12000 nucleotides in length. The genome has a g + c content of 43%[4].
Literature
Literature
- ↑ Kiveld, H.M., Kalkkinen, N. and Bamford, D.H. (2002). Bacteriophage PM2 has a protein capsid surrounding a spherical lipid-protein core. J. Virol., 76, 8169-8178.
- ↑ Kiveld, H.M., Männistö, R.H., Kalkkinen, N. and Bamford, D.H. (1999). Purification and protein composition of PM2, the first lipid-containing bacterial virus to be isolated. Virology, 262, 364-374.
- ↑ Harrison, S.C., Caspar, D.L., Camerini-Otero, R.D. and Franklin, R.M. (1971). Lipid and protein arrangement in bacteriophage PM2. Nat. New Biol., 229, 197-201.
- ↑ Männistö, R.H., Kivelä, H.M., Paulin, L., Bamford, D.H. and Bamford, J.K.H. (1999). The complete genome sequence of PM2, the first lipid-containing bacterial virus to be isolated. Virology, 262, 355-363.