Creutzfeldt-Jakob disease historical perspective

Creutzfeldt Jakob disease was first described in 1920-1921 by two German neurologists, Hans Gerhard Creutzfeldt and Alfons Maria Jakob. Creutzfeldt Jakob disease was first described in 1920-1921 by two German neurologists, Hans Gerhard Creutzfeldt and Alfons Maria Jakob. The term Creutzfeldt Jakob was first coined by Spielmeyer in 1922 in honor of Creutzfeldt and Jakob’s report. In 1997, Stanley B. Prusiner was awarded the Nobel Prize in physiology or medicine for his discovery of prions. In 2007, Laura Manuelidis, an American neuropathologist, and her colleagues described a virus-like particle without nucleic acid in less than 10% of the cells a scrapie-infected cell line and in a mouse cell line infected by a human Creutzfeldt Jakob disease agent.

• Creutzfeldt Jakob disease was first described in 1920-1921 by two German neurologists, Hans Gerhard Creutzfeldt and Alfons Maria Jakob.
• The term Creutzfeldt Jakob was first coined by Spielmeyer in 1922 in honor of Creutzfeldt and Jakob’s report.^[1]
• In 1997, Stanley B. Prusiner was awarded the Nobel Prize in physiology or medicine for his discovery of prions.
• In 2007, Laura Manuelidis, an American neuropathologist, and her colleagues described a virus-like particle without nucleic acid in less than 10% of the cells a scrapie-infected cell line and in a mouse cell line infected by a human Creutzfeldt Jakob disease agent.^[2]

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