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Creutzfeldt-Jakob disease historical perspective
Introduction
Overview
Overview
Creutzfeldt Jakob disease was first described in 1920-1921 by two German neurologists, Hans Gerhard Creutzfeldt and Alfons Maria Jakob. Creutzfeldt Jakob disease was first described in 1920-1921 by two German neurologists, Hans Gerhard Creutzfeldt and Alfons Maria Jakob. The term Creutzfeldt Jakob was first coined by Spielmeyer in 1922 in honor of Creutzfeldt and Jakob’s report. In 1997, Stanley B. Prusiner was awarded the Nobel Prize in physiology or medicine for his discovery of prions. In 2007, Laura Manuelidis, an American neuropathologist, and her colleagues described a virus-like particle without nucleic acid in less than 10% of the cells a scrapie-infected cell line and in a mouse cell line infected by a human Creutzfeldt Jakob disease agent.
Historical Perspective
Historical Perspective
- Creutzfeldt Jakob disease was first described in 1920-1921 by two German neurologists, Hans Gerhard Creutzfeldt and Alfons Maria Jakob.
- The term Creutzfeldt Jakob was first coined by Spielmeyer in 1922 in honor of Creutzfeldt and Jakob’s report.[1]
- In 1997, Stanley B. Prusiner was awarded the Nobel Prize in physiology or medicine for his discovery of prions.
- In 2007, Laura Manuelidis, an American neuropathologist, and her colleagues described a virus-like particle without nucleic acid in less than 10% of the cells a scrapie-infected cell line and in a mouse cell line infected by a human Creutzfeldt Jakob disease agent.[2]
References
References
- ↑ McKintosh, E.; Tabrizi, SJ.; Collinge, J. (2003). “Prion diseases”. J Neurovirol. 9 (2): 183–93. doi:10.1080/13550280390194082. PMID 12707849. Unknown parameter
|month=ignored (help) - ↑ Manuelidis L (February 6, 2007). “Cells infected with scrapie and Creutzfeldt-Jakob disease agents produce intracellular 25-nm virus-like particles”. Proceedings of the National Academy of Science. 104 (6): 1975–1970. PMID 17267596. Retrieved 2007-09-24. Unknown parameter
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]