Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Cryoglobulinemia natural history, complications and prognosis
Introduction
Overview
Overview
Natural History
Natural History
Complications
Complications
The complications of cryoglobulinemia are as follows:
- Rapidly progressive neuropathy
- Heart failure
- Digital ischemia threatening amputation
- Diffuse alveolar hemorrhage resulting in hemoptysis
- Respiratory failure
- Stroke
- End stage renal disease
Prognosis
Prognosis
Patients having severe manifestations of the disease such as pulmonary vasculitis, end-stage renal disease, cardiac vasculitis and central nervous system vasculitis have generally poor prognosis of the disease. The prognosis of cryoglobulinemia depends on the organ system involved and varies accordingly.
| Organ system involved | Survival rate |
|---|---|
| Glomerulonephritis | 79% |
| Pulmonary vasculitis | 22% |
| Central nervous system vasculitis | 66% |
| Gastrointestinal vasculitis | 67% |
| Cardiac vasculitis | 100% |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Feham Tariq, MD [2]