Cyclic vomiting syndrome natural history, complications and prognosis

There is little hard evidence of death as a result of the condition. However, in severe cases the fluid loss can lead to potentially life-threatening salt imbalances and extremely high blood pressure often develops during an attack. In underdeveloped countries it remains probable that CVS may contribute to mortality. In the developed world with adequate medical interventions most sufferers can be supported during an attack and will recover from the episode. After the average three year duration of Cyclic Vomiting Syndrome, 20 percent of patients were to seen to have developed migraines. Patients seemed to go through three stages: CVS, abdominal migraines which have similar characteristics as CVS then regular migraines.

On average 50% of patients require IV fluids. Whereas rotavirus gastroenteritis has less than 1% which require IV fluids. On average the cost of treatment, testing, work absences and leave per year can total in US dollars $17,000. Most children who have this disorder miss on average 24 school days a year, and will often need tutoring to catch up on their academic studies. The frequency of episodes is higher, for some people, during times of excitement, which often leads to many family events such as holidays, birthdays and vacations being disrupted. For adult sufferers the challenge of maintaining a career or full time employment is considerable. For all sufferers there are associated quality of life issues for not only the sufferer but also for close family members.

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