Cystic fibrosis laboratory findings

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shaghayegh Habibi, M.D.[2]

Overview

Immunoreactive trypsinogen (IRT) of serum is raised in newborns with cystic fibrosis and has been used as a screening test. Also Iron deficiency anemia is common in patients with cystic fibrosis.

Laboratory Findings

Immunoreactive trypsinogen (IRT) of serum is raised in newborns with cystic fibrosis and has been used as a screening test.^[1]
Complete blood count: Iron deficiency anemia is common in patients with cystic fibrosis and can be related to GI problems and chronic inflammation.^[2]

References

↑ Rock MJ, Mischler EH, Farrell PM, Bruns WT, Hassemer DJ, Laessig RH (1989). “Immunoreactive trypsinogen screening for cystic fibrosis: characterization of infants with a false-positive screening test”. Pediatr. Pulmonol. 6 (1): 42–8. PMID 2704582.
↑ Reid DW, Withers NJ, Francis L, Wilson JW, Kotsimbos TC (January 2002). “Iron deficiency in cystic fibrosis: relationship to lung disease severity and chronic Pseudomonas aeruginosa infection”. Chest. 121 (1): 48–54. PMID 11796431.

Overview