Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
DCTN4
Introduction
Dynactin subunit 4 is a protein that in humans is encoded by the DCTN4 gene.[1]
Further reading
Further reading
- Karki S, Tokito MK, Holzbaur EL (February 2000). “A dynactin subunit with a highly conserved cysteine-rich motif interacts directly with Arp1”. The Journal of Biological Chemistry. 275 (7): 4834–9. doi:10.1074/jbc.275.7.4834. PMID 10671518.
- Emond MJ, Louie T, Emerson J, Zhao W, Mathias RA, Knowles MR, Wright FA, Rieder MJ, Tabor HK, Nickerson DA, Barnes KC, Gibson RL, Bamshad MJ (July 2012). “Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis”. Nature Genetics. 44 (8): 886–9. doi:10.1038/ng.2344. PMC 3702264. PMID 22772370.
- Ayalon G, Davis JQ, Scotland PB, Bennett V (December 2008). “An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan”. Cell. 135 (7): 1189–200. doi:10.1016/j.cell.2008.10.018. PMID 19109891.
- Bingham JB, Schroer TA (February 1999). “Self-regulated polymerization of the actin-related protein Arp1”. Current Biology. 9 (4): 223–6. doi:10.1016/S0960-9822(99)80095-5. PMID 10074429.
- Lim CM, Cater MA, Mercer JF, La Fontaine S (May 2006). “Copper-dependent interaction of dynactin subunit p62 with the N terminus of ATP7B but not ATP7A”. The Journal of Biological Chemistry. 281 (20): 14006–14. doi:10.1074/jbc.M512745200. PMID 16554302.
- Boultwood J, Fidler C, Strickson AJ, Watkins F, Kostrzewa M, Jaju RJ, Müller U, Wainscoat JS (May 2000). “Transcription mapping of the 5q- syndrome critical region: cloning of two novel genes and sequencing, expression, and mapping of a further six novel cDNAs”. Genomics. 66 (1): 26–34. doi:10.1006/geno.2000.6193. PMID 10843801.