
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
DERL1
Introduction
Der1-like domain family, member 1, also known as DERL1, is a human gene.[1]
Further reading
Further reading
- Andersson B, Wentland MA, Ricafrente JY; et al. (1996). “A “double adaptor” method for improved shotgun library construction”. Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
- Yu W, Andersson B, Worley KC; et al. (1997). “Large-scale concatenation cDNA sequencing”. Genome Res. 7 (4): 353–8. PMID 9110174.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Clark HF, Gurney AL, Abaya E; et al. (2003). “The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment”. Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMID 12975309.
- Ota T, Suzuki Y, Nishikawa T; et al. (2004). “Complete sequencing and characterization of 21,243 full-length human cDNAs”. Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Lilley BN, Ploegh HL (2004). “A membrane protein required for dislocation of misfolded proteins from the ER”. Nature. 429 (6994): 834–40. doi:10.1038/nature02592. PMID 15215855.
- Ye Y, Shibata Y, Yun C; et al. (2004). “A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol”. Nature. 429 (6994): 841–7. doi:10.1038/nature02656. PMID 15215856.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)”. Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
- Katiyar S, Joshi S, Lennarz WJ (2006). “The retrotranslocation protein Derlin-1 binds peptide:N-glycanase to the endoplasmic reticulum”. Mol. Biol. Cell. 16 (10): 4584–94. doi:10.1091/mbc.E05-04-0345. PMID 16055502.
- Lilley BN, Ploegh HL (2006). “Multiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane”. Proc. Natl. Acad. Sci. U.S.A. 102 (40): 14296–301. doi:10.1073/pnas.0505014102. PMID 16186509.
- Ye Y, Shibata Y, Kikkert M; et al. (2006). “Inaugural Article: Recruitment of the p97 ATPase and ubiquitin ligases to the site of retrotranslocation at the endoplasmic reticulum membrane”. Proc. Natl. Acad. Sci. U.S.A. 102 (40): 14132–8. doi:10.1073/pnas.0505006102. PMID 16186510.
- Schulze A, Standera S, Buerger E; et al. (2006). “The ubiquitin-domain protein HERP forms a complex with components of the endoplasmic reticulum associated degradation pathway”. J. Mol. Biol. 354 (5): 1021–7. doi:10.1016/j.jmb.2005.10.020. PMID 16289116.
- Oda Y, Okada T, Yoshida H; et al. (2006). “Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation”. J. Cell Biol. 172 (3): 383–93. doi:10.1083/jcb.200507057. PMID 16449189.
- Schubert V, Da Silva JS, Dotti CG (2006). “Localized recruitment and activation of RhoA underlies dendritic spine morphology in a glutamate receptor-dependent manner”. J. Cell Biol. 172 (3): 453–67. doi:10.1083/jcb.200506136. PMID 16449195.
- Sun F, Zhang R, Gong X; et al. (2007). “Derlin-1 promotes the efficient degradation of the cystic fibrosis transmembrane conductance regulator (CFTR) and CFTR folding mutants”. J. Biol. Chem. 281 (48): 36856–63. doi:10.1074/jbc.M607085200. PMID 16954204.
- Crawshaw SG, Cross BC, Wilson CM, High S (2007). “The oligomeric state of Derlin-1 is modulated by endoplasmic reticulum stress”. Mol. Membr. Biol. 24 (2): 113–20. doi:10.1080/09687860600988727. PMID 17453418.
