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DNA replication-related element gene transcriptions

Introduction

Associate Editor(s)-in-Chief: Henry A. Hoff

“The promoters of Drosophila genes encoding DNA replication-related proteins contain transcription regulatory elements consisting of an 8-bp palindromic DNA replication-related element (DRE) sequence (5′-TATCGATA).”[1]

Consensus sequences

Consensus sequences

DNA replication-related element (DRE) sequence is 5′-TATCGATA-3′.[1]

Samplings

Samplings

Main article: Model samplings

Samplings

Copying the consensus of the DRE: 5′-TATCGATA-3′ and putting the sequence in “⌘F” finds no locations for this sequence in any A1BG direction as can be found by the computer programs.

For the Basic programs testing consensus sequence 5′-TATCGATA-3′ (starting with SuccessablesDRRE.bas) written to compare nucleotide sequences with the sequences on either the template strand (-), or coding strand (+), of the DNA, in the negative direction (-), or the positive direction (+), the programs are, are looking for, and found:

  1. negative strand, negative direction, looking for 5′-TATCGATA-3′, 0.
  2. negative strand, positive direction, looking for 5′-TATCGATA-3′, 0.
  3. positive strand, negative direction, looking for 5′-TATCGATA-3′, 0.
  4. positive strand, positive direction, looking for 5′-TATCGATA-3′, 0.
  5. complement, negative strand, negative direction, looking for 5′-ATAGCTAT-3′, 0.
  6. complement, negative strand, positive direction, looking for 5′-ATAGCTAT-3′, 0.
  7. complement, positive strand, negative direction, looking for 5′-ATAGCTAT-3′, 0.
  8. complement, positive strand, positive direction, looking for 5′-ATAGCTAT-3′, 0.
  9. inverse complement, negative strand, negative direction, looking for 5′-TATCGATA-3′, 0.
  10. inverse complement, negative strand, positive direction, looking for 5′-TATCGATA-3′, 0.
  11. inverse complement, positive strand, negative direction, looking for 5′-TATCGATA-3′, 0.
  12. inverse complement, positive strand, positive direction, looking for 5′-TATCGATA-3′, 0.
  13. inverse negative strand, negative direction, looking for 5′-ATAGCTAT-3′, 0.
  14. inverse negative strand, positive direction, looking for 5′-ATAGCTAT-3′, 0.
  15. inverse positive strand, negative direction, looking for 5′-ATAGCTAT-3′, 0.
  16. inverse positive strand, positive direction, looking for 5′-ATAGCTAT-3′, 0.
Acknowledgements

Acknowledgements

The content on this page was first contributed by: Henry A. Hoff.

See also

See also

References

References

  1. ↑ 1.0 1.1 Fumiko Hirose, Masamitsu Yamaguchi, Akio Matsukage (September 1999). “Targeted Expression of the DNA Binding Domain of DRE-Binding Factor, a Drosophila Transcription Factor, Attenuates DNA Replication of the Salivary Gland and Eye Imaginal Disc”. Molecular and Cellular Biology. 19 (9): 6020–6028. doi:10.1128/MCB.19.9.6020. PMID 10454549. Retrieved 4 September 2020.
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