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Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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DRESS syndrome epidemiology and demographics

Introduction

Overview

Overview

The incidence of DRESS syndrome is approximately 10 to 100 per 100,000 drug exposures. The case-fatality rate of DRESS syndrome is approximately 10%. DRESS syndrome has been reported among patients of all ages with no gender or racial predilection.

Epidemiology and Demographics

Epidemiology and Demographics

Incidence

  • The incidence of DRESS syndrome is approximately 10 to 100 per 100,000 drug exposures.[1]

Case-Fatality Rate

  • The case-fatality rate of DRESS syndrome is approximately 10%.

Age

  • DRESS syndrome affects patients of all ages and has been reported among pediatric, adult, and elderly patients.[1]
  • In modest-sized observational studies and case series:
  • The median age for the development of DRESS syndrome is approximately 40-50 years among adult patients.[2][3]
  • The median age for the development of DRESS syndrome is approximately 10-12 years among pediatric patients.[4]

Gender

  • There is no gender predilection to the development of DRESS syndrome.

Race

  • There is no racial predilection to the development of DRESS syndrome.
References

References

  1. ↑ 1.0 1.1 Fiszenson-Albala F, Auzerie V, Mahe E, Farinotti R, Durand-Stocco C, Crickx B; et al. (2003). “A 6-month prospective survey of cutaneous drug reactions in a hospital setting”. Br J Dermatol. 149 (5): 1018–22. PMID 14632808.
  2. ↑ Cacoub P, Musette P, Descamps V, Meyer O, Speirs C, Finzi L; et al. (2011). “The DRESS syndrome: a literature review”. Am J Med. 124 (7): 588–97. doi:10.1016/j.amjmed.2011.01.017. PMID 21592453.
  3. ↑ Chen YC, Chiu HC, Chu CY (2010). “Drug reaction with eosinophilia and systemic symptoms: a retrospective study of 60 cases”. Arch Dermatol. 146 (12): 1373–9. doi:10.1001/archdermatol.2010.198. PMID 20713773.
  4. ↑ Carroll MC, Yueng-Yue KA, Esterly NB, Drolet BA (2001). “Drug-induced hypersensitivity syndrome in pediatric patients”. Pediatrics. 108 (2): 485–92. PMID 11483822.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yazan Daaboul, M.D., Serge Korjian M.D.