
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions β written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
De Quervain's thyroiditis natural history, complications and prognosis
Introduction
Overview
Overview
De Quervain’s thyroiditis develops after a viral prodrome and presents as painful thyroid gland with symptoms of thyrotoxicosis. It further leads to a euthyroid phase and eventually hypothyroid phase before the complete resolution of the disease. Complications include hypothyroidism and rarely, esophageal or tracheal compression.
Natural history, complications, and prognosis
Natural history, complications, and prognosis
Natural history
De Quervain’s thyroiditis develops after a viral prodrome and presents as painful thyroid gland with symptoms of thyrotoxicosis. It further leads to a euthyroid phase and eventually hypothyroid phase before the complete resolution of the disease.[1][2][3]
1. Prodromal stage
It includes:
- Low-grade fever and viral flu-like symptoms, such as sore throat, myalgia, arthralgia, and malaise.
- High-grade fever and neck pain with a tender and diffuse thyroid gland enlargement follow flu-like symptoms.
2. Hyperthyroid stage
It follows the prodromal stage and includes the symptoms of thyrotoxicosis such as:
- Tachycardia and tremors
- Irritability and nervousness
3. Euthyroid stage
Thyrotoxic stage is followed by a 1β3-week period of euthyroid phase.
4. Hypothyroid stage
The transient hypothyroid stage lasts for 6-12 months.
- Rarely, the hypothyroid stage may persist for a longer duration.
Complications
Complications that can develop as a result of de Quervain’s thyroiditis are:[1][2][3]
- Hypothyroidism
- Tracheal compression
- Esophageal compression
Prognosis
Prognosis of de Quervain’s thyroiditis is usually good.
References
References
- β 1.0 1.1 “Thyroiditis β NEJM”.
- β 2.0 2.1 Engkakul P, Mahachoklertwattana P, Poomthavorn P (2011). “EponymΒ : de Quervain thyroiditis”. Eur. J. Pediatr. 170 (4): 427β31. doi:10.1007/s00431-010-1306-4. PMIDΒ 20886353.
- β 3.0 3.1 Leibovitch G, Maaravi Y, Shalev O (1989). “Severe facial oedema and glossitis associated with mianserin”. Lancet. 2 (8667): 871β2. PMIDΒ 2571803.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]
