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Demeclocycline hydrochloride description
Introduction
| Demeclocycline hydrochloride |
|---|
| DEMECLOCYCLINE HYDROCHLORIDE® FDA Package Insert |
| Description |
| Clinical Pharmacology |
| Microbiology |
| Indications and Usage |
| Contraindications |
| Warnings and Precautions |
| Adverse Reactions |
| Drug Interactions |
| Overdosage |
| Dosage and Administration |
| How Supplied |
| Labels and Packages |
Description
Description
Demeclocycline hydrochloride is an antibiotic isolated from a mutant strain of Streptomyces aureofaciens. Chemically it is 7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12, 12a-pentahydroxy-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride. The structural formula is:
The molecular weight is 501.32 and the empirical formula is C21H21CIN2O8•HCI.
Each film-coated tablet contains demeclocycline hydrochloride 150 mg or 300 mg. In addition, each tablet contains the following inactive ingredients: alginic acid, colloidal silicon dioxide, crosscarmellose sodium, lactose monohydrate, microcrystalline cellulose, magnesium stearate, and povidone. The film coating material, contains FD&C Red #40, hypromellose 3cP, hypromellose 6cP, hypromellose 50cP, macrogol, polydextrose, titanium dioxide and triacetin.[1]
References
References
- ↑ “DEMECLOCYCLINE HYDROCHLORIDE TABLET, FILM COATED [GLOBAL PHARMACEUTICALS, DIVISION OF IMPAX LABORATORIES, INC.]”. Text ” accessdate” ignored (help)
Adapted from the FDA Package Insert.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]