Dermatitis Herpetiformis (also called Duhring’s disease), is a chronic itchy rash which is frequently associated with Celiac Disease. The rash is made of papules and vesicles which are present on different parts of the body mostly commonly on neck, trunk, buttocks and knees. It is an autoimmune mediated skin condition, which is IgA mediated reaction and is associated with gluten sensitivity of small bowel. There is presence of antibodies which leads to positive serology test results.

Dermatitis herpetiformis is associated with high prevalence of other autoimmune diseases.

The most important risk factor in the development of this rash of dermatitis herpetiformis is presence of Gluten in the diet of genetically susceptible individuals. see Dermatitis herpetiformis pathophysiology