Desmoid tumor diagnostic study of choice

Definitive diagnosis of a desmoid tumor can only be established by histological examination of a biopsy specimen. Electron microscopy can be done which shows spindle cells of desmoids appearing as myofibroblasts.

• Biopsy is the most important and conclusive diagnostic procedure for desmoid tumor
• After biopsy, definitive diagnosis must be established on histopathologic analysis
• Electron microscopy is performed to obtain further clarity and confirmation for the diagnosis
• Spindle cells of desmoid tumors appear to be myofibroblasts on electron microscopy which represents an abnormal proliferation of myofibroblasts, which normally disappear gradually during the later stages of wound healing