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Desmoid tumor epidemiology and demographics

Introduction

Overview

Overview

Desmoid tumor accounts for 0.03% of all tumors and less than 3% of all the soft tissue tumors. It affects 1 to 2 per 500,000 people worldwide. Incidence of desmoid tumor is approximately two to four per million population per year in general population. Familial desmoids are present in 10% to 25% of FAP patients. Gender ratio is 2:1 for females to males and commonly affects individuals between 20 to 60 years of age.

Epidemiology and Demographics

Epidemiology and Demographics

Incidence

Prevalence

Gender

  • Female are more commonly affected by desmoid tumor than male.[10]
  • The female of fertile age to male ratio is approximately 2:1.
  • Incidence is the same in both genders in children.

Age

  • Desmoid tumor commonly affects individuals between 20 to 60 years of age.[2][11]
  • Desmoid tomur commonly affects 30 to 40 years.
Reference

Reference

  1. ↑ Reitamo JJ, Häyry P, Nykyri E, Saxén E (1982). “The desmoid tumor. I. Incidence, sex-, age- and anatomical distribution in the Finnish population”. Am J Clin Pathol. 77 (6): 665–73. PMID 7091046.
  2. ↑ 2.0 2.1 Desmoid tumor. Dr Tim Luijkx and Radswiki et al.Radiopaedia 2015.http://radiopaedia.org/articles/desmoid-tumour. Accessed on January 21, 2016
  3. ↑ Bertario L, Russo A, Sala P, Eboli M, Giarola M, D’amico F; et al. (2001). “Genotype and phenotype factors as determinants of desmoid tumors in patients with familial adenomatous polyposis”. Int J Cancer. 95 (2): 102–7. PMID 11241320.
  4. ↑ Friedl W, Caspari R, Sengteller M, Uhlhaas S, Lamberti C, Jungck M; et al. (2001). “Can APC mutation analysis contribute to therapeutic decisions in familial adenomatous polyposis? Experience from 680 FAP families”. Gut. 48 (4): 515–21. PMC 1728231. PMID 11247896.
  5. ↑ Ferenc T, Sygut J, KopczyÅ„ski J, Mayer M, Latos-BieleÅ„ska A, Dziki A; et al. (2006). “Aggressive fibromatosis (desmoid tumors): definition, occurrence, pathology, diagnostic problems, clinical behavior, genetic background”. Pol J Pathol. 57 (1): 5–15. PMID 16739877.
  6. ↑ Leal RF, Silva PV, Ayrizono Mde L, Fagundes JJ, Amstalden EM, Coy CS (2010). “Desmoid tumor in patients with familial adenomatous polyposis”. Arq Gastroenterol. 47 (4): 373–8. PMID 21225148.
  7. ↑ Fisher C, Thway K (2014). “Aggressive fibromatosis”. Pathology. 46 (2): 135–40. doi:10.1097/PAT.0000000000000045. PMID 24378386.
  8. ↑ Schiessling S, Kihm M, Ganschow P, Kadmon G, Büchler MW, Kadmon M (2013). “Desmoid tumour biology in patients with familial adenomatous polyposis coli”. Br J Surg. 100 (5): 694–703. doi:10.1002/bjs.9053. PMID 23334997.
  9. ↑ Fallen T, Wilson M, Morlan B, Lindor NM (2006). “Desmoid tumors — a characterization of patients seen at Mayo Clinic 1976-1999”. Fam Cancer. 5 (2): 191–4. doi:10.1007/s10689-005-5959-5. PMID 16736290.
  10. ↑ Mankin HJ, Hornicek FJ, Springfield DS (2010). “Extra-abdominal desmoid tumors: a report of 234 cases”. J Surg Oncol. 102 (5): 380–4. doi:10.1002/jso.21433. PMID 19877160.
  11. ↑ Economou, Athanasios; Pitta, Xanthi; Andreadis, Efstathios; Papapavlou, Leonidas; Chrissidis, Thomas (2011). “Desmoid tumor of the abdominal wall: a case report”. Journal of Medical Case Reports. 5 (1): 326. doi:10.1186/1752-1947-5-326. ISSN 1752-1947.

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sara Mohsin, M.D.[2]